Zhude Tu Selected Research

Vesicular Acetylcholine Transport Proteins (Vesicular Acetylcholine Transporter)

11/2021	In vitro characterization of [3H]VAT in cells, animal and human brain tissues for vesicular acetylcholine transporter.
2/2020	The impact of dopamine D2-like agonist/antagonist on [18F]VAT PET measurement of VAChT in the brain of nonhuman primates.
11/2018	Radiosynthesis and evaluation of a fluorine-18 labeled radioligand targeting vesicular acetylcholine transporter.
1/2018	Kinetic modeling of [18 F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non-human primate brain.
6/2017	Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate.
4/2015	In vitro and ex vivo characterization of (-)-TZ659 as a ligand for imaging the vesicular acetylcholine transporter.

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Zhude Tu Research Topics

Disease

10	Neoplasms (Cancer) 11/2020 - 02/2006
6	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2016
6	Parkinson Disease (Parkinson's Disease) 02/2021 - 08/2012
6	Inflammation (Inflammations) 11/2020 - 08/2015
6	Breast Neoplasms (Breast Cancer) 03/2014 - 07/2005
4	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2022 - 02/2016
4	Neuroinflammatory Diseases 01/2022 - 05/2017
3	Cognitive Dysfunction 01/2022 - 11/2018
3	Dementia (Dementias) 01/2018 - 04/2015
3	Multiple Sclerosis 01/2018 - 10/2016
2	Schizophrenia (Dementia Praecox) 01/2022 - 01/2016
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2018 - 05/2017
2	Melanoma (Melanoma, Malignant) 03/2014 - 02/2006
2	Prostatic Neoplasms (Prostate Cancer) 10/2013 - 02/2006
1	Amyloidosis 01/2022
1	Stroke (Strokes) 02/2021
1	Thrombosis (Thrombus) 02/2021
1	Bacterial Infections (Bacterial Infection) 01/2021
1	Communicable Diseases (Infectious Diseases) 01/2021
1	Animal Disease Models 01/2019
1	Tauopathies 02/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Atherosclerotic Plaque (Atheroma) 01/2018
1	Atherosclerosis 01/2018
1	Neointima 01/2017
1	Hyperplasia 01/2017
1	Vascular System Injuries 01/2017
1	Dystonia (Limb Dystonia) 01/2016
1	Central Nervous System Diseases (CNS Diseases) 08/2015
1	Carcinoma (Carcinomatosis) 01/2013
1	Disease Progression 01/2013
1	Opioid-Related Disorders (Opiate Addiction) 04/2011
1	Nervous System Diseases (Neurological Disorders) 03/2011
1	Pancreatic Neoplasms (Pancreatic Cancer) 11/2010
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 02/2006
1	Necrosis 07/2005

Drug/Important Bio-Agent (IBA)

8	Sphingosine-1-Phosphate ReceptorsIBA 01/2021 - 08/2015
8	LigandsIBA 04/2018 - 07/2005
7	Cholinergic Agents (Cholinergics)IBA 11/2021 - 04/2015
7	Biomarkers (Surrogate Marker)IBA 10/2020 - 03/2014
6	Vesicular Acetylcholine Transport Proteins (Vesicular Acetylcholine Transporter)IBA 11/2021 - 04/2015
6	sigma-2 receptorIBA 03/2014 - 02/2006
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2018
3	SynucleinsIBA 01/2018 - 08/2012
3	benzamideIBA 01/2013 - 06/2006
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2022 - 11/2020
2	Biological ProductsIBA 11/2020 - 12/2010
2	Pharmaceutical PreparationsIBA 01/2019 - 04/2011
2	LipopolysaccharidesIBA 04/2018 - 05/2017
2	Purinergic P2X7 ReceptorsIBA 02/2018 - 05/2017
2	Carbon-11IBA 01/2018 - 07/2005
2	Fluorine-18IBA 01/2018 - 12/2010
2	Monoclonal AntibodiesIBA 10/2013 - 11/2012
1	Messenger RNA (mRNA)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	pyrazoleIBA 02/2021
1	apixabanIBA 02/2021
1	AnticoagulantsIBA 02/2021
1	Adenosine Diphosphate (ADP)IBA 11/2020
1	Phosphotransferases (Kinase)IBA 11/2020
1	sphingosine kinaseIBA 11/2020
1	alpha-SynucleinIBA 11/2018
1	SEW2871IBA 04/2018
1	TZ6019IBA 02/2018
1	salicylhydroxamic acid (SHAM)IBA 05/2017
1	ElementsIBA 05/2017
1	N- (2- chloro- 3- (trifluoromethyl)benzyl)- N- methyl- 5- oxopyrrolidine- 2- carboxamideIBA 05/2017
1	Apolipoproteins E (ApoE)IBA 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 01/2016
1	CaspasesIBA 03/2014
1	Fluorescent Dyes (Fluorescent Probes)IBA 10/2013
1	vorozoleIBA 01/2013
1	Bromodeoxyuridine (BrdU)IBA 01/2013
1	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 01/2013
1	Bexarotene (LGD1069)FDA Link 01/2013
1	CarbohydratesIBA 11/2012
1	AntigensIBA 11/2012
1	Polysaccharides (Glycans)IBA 11/2012
1	AntibodiesIBA 11/2012
1	Buprenorphine (Subutex)FDA LinkGeneric 04/2011
1	Dopamine Receptors (Dopamine Receptor)IBA 03/2011
1	Iodine-125IBA 12/2010
1	SV119IBA 11/2010
1	Gemcitabine FDA Link 11/2010
1	FluorineIBA 07/2007
1	N- (oxo- 5,6- dihydrophenanthridin- 2- yl)- N,N- dimethylacetamide hydrochlorideIBA 07/2005

Therapy/Procedure

5	Therapeutics 07/2022 - 07/2011
1	Intravenous Injections 01/2021